NEW Patent CD for Controlled release tramadol

NEW Patent CD for Controlled release tramadol




Following is a sample of the information contained on this CD: The present invention relates to a controlled release preparation for oral administration, to processes for its preparation and to its medical use. In particular, (lie invention relates to a controlled release preparation comprising tramadol or a pharmaceutically acceptable salt thereof. Tramadol, which has the chemical name (+)-trans-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl) cyclohexanol, is an orally active opioid analgesic. Conventional release preparations in the form of capsules, drops and suppositories containing tramadol, or more particularly its hydrochloride salt, have been commercially available for many years for use in the treatment of moderate to severe pain; Such preparations, however, do not provide a controlled release of the tramadol. Moreover, despite tramadol’s long-standing use, controlled release preparations for oral administration containing tramadol as active ingredient have not even previously been described in the literature. It is an object of the present invention to provide an oral controlled release tramadol preparation suitable for at least twelve-hourly (e.g. up to twenty-four hourly) administration for the treatment of pain. The present invention therefore provides a controlled release preparation comprising tramadol or a pharmaceutically acceptable salt thereof for oral administration. Suitable pharmaceutically acceptable salts of tramadol for use according to the present invention are those conventionally known in the art such as pharmaceutically acceptable acid addition salts. The hydrochloride salt is particularly preferred. A controlled release preparation according to the present invention is one that achieves slow release of a drug over an extended period of time, thereby extending the duration of drug action over that achieved by conventional delivery. Preferably such a preparation maintains a drug concentration in the blood within the

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    BIOFREEZE with ILEX Pain Relieving Gel 32 oz Pump Bottle




    BIOFREEZE was created by Dr. Dann

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      Mind Over Back Pain

      Mind Over Back Pain



      User Ratings and Reviews

      5 Stars Any structural ache? A must-read as a second opinion!
      The older I get, the more I need to believe in second (health status) opinions? This book encourages believing in the power of one’s own body. This is not hokus-pokus. This is based on the healing power of the body by using mind (emotion) and body. The book is witten by a well-established MD, who is questioning “standard” practices.

      5 Stars It really works!
      Like many other reviewers, I’m here to tell you that Dr. John Sarno’s theory that the majority of chronic back pain is caused by stress will set you free.

      I found myself during a particularly high stress period experiencing numbness and pain in my right arm. Within a month I was immobilized by it, living on Vicodin.

      It took about 6 weeks of reading and re-reading the book to get to the point where I no longer needed pain killers. I had been told I had a bulging disc and would require surgery. Dr. Sarno saved me from surgery.

      Yes…. really.

      If you are suffering from chronic back pain I urge you to read this book. The realization that we are doing it to ourselves – once it sinks in – is enough to end your pain and change your life.

      I still feel a little pain on occassion – always during times of stress or fear – and I need only remind myself of what I learned from Dr. Sarno and it goes away. It is not an instant cure, and you DO need to read and re-read until your mind accepts the concept and your body falls in line…

      but it WORKS!!

      4 Stars This is a good start!
      When I first read Dr. Sarno’s Mind Over Back Pain I developed a good understanding of the mind/body connection. It was his Healing Back Pain that give me a deeper understanding of how repressed anger, anxiety, and frustration can cause pain. At the time I was disabled with back, leg, neck, and hand pain, and quite disappointed and frustrated with the treatments I had recieved.

      Dr. Sarno’s explanation answered all my questions about my condition and fit perfectly well with all the crucial research information I had discovered. Although Dr. Sarno’s guidelines seemed useful, I felt the need for more concrete steps and a faster recovery time. As a father of two, I wanted to get well as quickly as possible.

      So I designed an effective nine-step plan for rapid recovery based on techniques used by Olympic athletes. The rapid recovery plan helped me improve immediately and recover shortly after. Those with herniated discs as well as carpal tunnel syndrome have recovered rapidly using these techniques.

      After my recovery I wanted to share my story and the recovery plan with all those suffering needlessly from back and neck pain. In addition to conducting seminars and workshops for the University of California, CIGNA, and other organizations, I wrote Rapid Recovery from Back and Pain: A Nine-Step Recovery Plan which provides crucial research on back and neck pain and many cases of rapid recovery as well as a section for designing a personal rapid recovery plan. Rapid Recovery from Back and Neck Pain is availabe at Amazon.com.

      5 Stars This book changed my life.
      Yes, I am serious. No hyperbole. I had just moved to North Carolina from Florida in 1986, but was back in Florida on business. Because I still had a month or more on my membership at a local fitness/rehab center, I went there to work out each day of my visit. On one particular day, I was aching pretty badly from the long-running, chronic back pain I had had for more than seven years.

      At the time, it was attributed to a car accident in which I totaled my car. Seemed logical. But, that day in the Florida fitness center, I picked up a magazine (I think it was New York magazine, but it might have been The New Yorker) and read an article about back pain. As I read it and peddled on a stationary bike, I was experiencing constant back pain. One reference in the article was to Dr. Sarno and his views on this subject. I didn’t realize at the time how I was internalizing his theory.

      That evening, I was at a friend’s home waiting for them to arrive home from work. I thought about what I had read and it struck me like the proverbial thunderbolt. Here I was, about to sit down on a couch and I realized that I could test Sarno’s idea. Instead of my typical posturing and holding my back to avoid pain as I tried to sit, I literally flopped and fell into the seat, throwing caution to the wind. I figured, what have I got to lose? A bit more pain? Well, there was no pain. None. It absolutely shocked me. I laughed out loud. Of course, I then got up, but noticed that I slipped into my habitual holding tight as if my back had a steel rod running up and through it. That hurt! That made me realize that was “me” and not a skeletal or other physical problem that I had. I then had something remarkable happen. The muscles in my back and upper buttocks literally relaxed in a wave of release. This was all about Sarno’s theory, folks. And it worked for me. I bought Dr. Sarno’s book before I left Florida.

      I went back to my new home in NC and at my next chiropractic session (I had been to M.D.’s, physical therapists, chiropractors, and massage therapists since the onset of the pain), I waved the book in the air and proclaimed what I had learned. She wanted no part of it. And so, that was my last chiropractic session with her or any chiropractor for this so-called chronic lower back pain. Ever since then, I’ve been able to manage any twinges of recurring pain because they are few and far apart and eliminated through stress management and relaxation. I don’t know where Dr. Sarno is, but he changed my life and I thank him for it.

      5 Stars John Sarno – Back Pain
      I have read all of Dr. Sarno’s books and for anyone that has back problems, I would highly recommend them. I think you will be surprised as to the medical “findings” that are revealed by Dr. Sarno. Mind of matter – the mind is a definite asset in handling pain and his books will help you. Thanks…..Skip

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        Healing Back Pain The Mind Body Connection

        Healing Back Pain The Mind Body Connection




        Healing Back Pain promises permanent elimination of back pain without drugs, surgery, or exercise. It should have been titled Understanding TMS Pain, because it discusses one particular cause of back pain–Tension Myositis Syndrome (TMS)–and isn’t really a program for self-treatment, with only five pages of action plan (and many more pages telling why conventional methods don’t work). According to John E. Sarno, M.D., TMS is the major cause of pain in the back, neck, shoulders, buttocks, and limbs–and it is caused not by structural abnormalities but by the mind’s effort to repress emotions. He’s not saying that your pain is all in your head; rather, he’s saying that the battle going on in your mind results in a real physical disorder that may affect muscles, nerves, tendons, or ligaments. An injury may have triggered the disorder, but is not the cause of the amount or intensity of the resulting pain. According to Sarno, the mind tricks you into not facing repressed emotion by making you focus on pain in the body. When this realization sinks in (“and it must sink in, for mere intellectual appreciation of the process is not enough”), the trick doesn’t work any more, and there’s no need for the pain. (Healing Back Pain should not be used for self-diagnosis. Always consult a physician for chronic or acute back pain.) –Joan Price

        User Ratings and Reviews

        5 Stars Got rid of my sciatica and back spasms!
        I remember my first true back spasm in college: I bent down to get something out of a drawer and for no apparent reason, my back “snapped.” I was walking crooked for days. I tried laying still, struggling through some sit ups (I recalled a friend in high school who had been given such “back strengthening” exercises for his back pain) and just hoping it would go away. From time to time, my back would “go out” again and I’d suffer for a few weeks as it slowly healed and I tried to take it easy. One time, my back hurt so bad, I had to take several minutes just to get out of bed!

        In 2005 I was vacationing at my parents’. I spent many hours on the floor playing games with my brothers and my kids. I noticed a slight numbness in my leg.At first I thought it was constantly falling asleep from being cross-legged on the floor for hours. It gradually grew and traveled down my leg until I had full blown sciatica (with lower back pain too)! One day, browsing at Barnes & Noble, I was looking for some sort of book about back pain and how to get rid of it. I found this book. I read through it quickly and a day or two after I finished it, the sciatica was completely gone. It has never come back and the worst I ever get is a “stiff” back which is easily dealt with through the principles of the book.

        The essential thesis is this: Back pain (as well as several other ailments) is caused by an unconscious denial of blood to a certain part of your body. Your brain does this subconsciously to take you away from dealing with the things that are actually causing stress, anger and anxiety. This is NOT saying that the pain is “all in your head.” It’s an acknowledgment of real pain. But that pain has a cause. The essential steps for dealing with the pain are: (1) Living, working, acting normally as if your back is not injured, that is, not favoring it, “going easy” on it, etc. and (2) identifying what is causing you anger or stress and dealing consciously as necessary with the issue.

        After I read that, I actually could trace the beginning of my pre-sciatica numbness to an email I had gotten regarding work which had really made me angry. Once I realized what I was really upset about, the pain was gone. In the days since I’ve read this book, my back has only once or twice really “snapped” and I immediately began going through the events and frustrations of my mind. The pain is usually gone within a day. Even that is quite rare now and whenever I have a stiff back, I simply do the same thing: run a mental catalog of stressful or anger-inducing items while doing nothing to favor or “baby” the back and the pain fades.

        The author, Dr. Sarno, describes this important mind-body connection in a way that poles some fun at current medical practice (so many ways to treat a bad back? Why? Because who knows what will work? The problem isn’t the back! It’s the things causing your brain to mess with your back!). Dr. Sarno can get a little Freudian sometimes and even recommends deep Freudian therapy to bring out the worst of the issues that your brain might be trying to block. But other than that, I think his thesis is a solid one. It’s certainly attested to by others but I have the best evidence of its truth: It worked. Plain and simple. I no longer get nasty back spasms that leave me walking crookedly for weeks on end. And when my back does get stiff, then that is now a signal that I need to run a mental check and deal with the things that are bothering me that my mind is avoiding.

        I’ve read and used the book. It’s worked for my wife. The principles have been useful with the kids (“growing” pains) and I’ve ordered and given copies to friends. Call it bunk if you like but the thesis sounds good to me and it works!

        1 Star Not buying the hype…
        Give me a break! Gentle exercise, massage and learning proper biomechanics is working. Believing there are emotions I am not addressing just doesn’t make sense to me. I don’t hold anger in. Either I journal, meditate, or read somebody the riot act when I am angry! I don’t give it a chance to do me harm. As far as I’m concerned, I can’t see how unacknowledged anger in my life is causing me back pain. I seem to be one of those who don’t fit the profile of the fuming, seething individual who has emotional turmoil and indeed has lost touch with his/her emotions. For that readership, I guess they give the book five stars.

        Save your money and go buy a nice journal instead. Do you a world of good.

        5 Stars This book is the answer i’ve been looking for!
        2 weeks I’ve waited for this book.

        1 week it took me to read it.

        7 yaers of agony and pain ended last week after reading this book.

        I can’t believe it!

        Pain that has been my evel companion and dictated every aspect of my life – gone!!!

        Sometimes I feel the pain trying to come back, sneak on me, but now I know why it’s there and I can make it disappear again after 5 minutes or so.

        This is unreal. Its almost ridiculous.

        I am 33 years old, and for the first time in 7 years – I fill young, and free.

        This book is worth more then 7000$ – the amount I payed on painkillers and alternative medicine so far, and no doubt – would have kept on paying for many years to come.

        If you ever had back or neck pain that crippled you, while doctors telling you that you have a herniated disc but can’t explain why it hurts so much, or why you are in pain most of the time, even while sitting down – Well, this is the book for you.

        You don’t need to be in pain.

        You don’t need to be depressed anymore.

        Just read this book and be open to what it has to say to you, think about it, really think.

        I did and it changed my life, and I recommand this book to anyone who suffers from back & neck pain, and forever greatfull to John E. Sarno for giving me my life back <3.

        5 Stars The Best Treatment Formula
        I am a professor at a medical school. I have suffered from chronic lower back pain since my 20′s. This book was the best “treatment” I have ever tried. But, it helps to read it more than once. Remember that most of us do not grasp all of the important ideas with just one reading. Also, I highly recommend Dr. Sarno’s other books.

        5 Stars The Mind-Body Connection
        I first heard of Dr. John Sarno in Dr. Andrew Weil’s book “Spontaneous Healing : How to Discover and Embrace Your Body’s Natural Ability to Maintain and Heal Itself. I believed I had “slipped a disk” while back-packing in Australia. While I was scuba-diving the Great Barrier Reef (and doing my best to pretend I was not in crippling pain) the pain deepened into sciatica. I could barely walk. Wherever I was, at the airport, on the boardwalk, I had to lay on the ground and curl up into a ball in order to walk another few minutes. In New Zealand, as I was hitchhiking from Christchurch to Auckland on big-rig trucks, a physical therapist gave me some exercises he said I’d have to do for the rest of my life. After a year or so of helping, the exercises stopped working. I was so afraid I’d have to have back surgery and/or be crippled for the rest of my life. When I read about Dr. Sarno’s deconstructing the emotional and stress-related mind-body connection in the majority of back pain syndromes, I started to mentally investigate my own back spasms. What was I thinking about when the back pain started? I started to see my own pattern of worry – that I had been attributing to my sitting position in the car, or my shoes for instance to my stresses and deepest fears. As I read more of Dr. Sarno’s carefully detailed investigation into Tension Myositis Syndrome (TMS), my back pain gradually subsided as I learned the mechanisms of TMS, and deconstructed my own experience of back pain. A year later, I rarely experience back pain, and when I do it’s very minor and just a sign that I need to relax and take care of myself. I can even wear high-heeled shoes and go back-packing again (not at the same time), and all manner of bending over and sitting positions are no problem. I’ve even taken up hula-hooping! One should certainly investigate TMS before considering back surgery. TMS may not be a diagnosis accepted by the entire medical community, nonetheless, Dr Sarno’s approach *WORKS* and it could work for you. It’s as easy as reading a book, critically deconstructing your own experience, and changing the way you deal with stress. I’ll add that reading a book is inexpensive and harmless. Spinal surgery is not. This is even my 2nd copy of this book, because I purchased a copy for someone I cared about who had back pain. I recommend this book to *everyone!!!* Best wishes… :) MT

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          Decade 6333 Cadet Back Support Black Large

          Decade 6333 Cadet Back Support Black Large



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